Ventilator Associated Pneumonia (VAP) Antibiogram of Dr. Soebandi Hospital, Jember In 2019
DOI:
https://doi.org/10.67580/medixis.v1i1.89Keywords:
Pneumonia, Antibiotics, AntibiogramAbstract
Ventilator-Associated Pneumonia (VAP) is a type of nosocomial infection that occurs after 48-72 hours of endotracheal intubation with a high mortality rate and is most commonly seen in hospital ICUs The high mortality rate in VAP cases could, among other things, be caused by the emergence of multidrug resistant (MDR) species that may be caused by irrational use of antibiotics. The existence of an antibiogram is expected to solve the problem. This study aimed to form a VAP antibiogram of dr. Soebandi Hospital in Jember City, East Java, Indonesia, can be used to reference rational therapy.This research is a descriptive study using secondary data obtained from medical records. The data will be collected and analyzed in a univariate manner, and then the analysis results will be displayed in graphs and tables. The number of samples used was 37 medical record data that matched the criteria and obtained 39 isolates. Of the 39 isolates, 22 different types of bacteria were obtained. These bacteria come from 7 different families. In addition, of the 39 identified types of bacteria, 29 of them were Gram-negative bacteria (74%), the remaining 10 were Gram-positive bacteria (26%). The antibiotics with the most useful and have a sensitivity level of more than 50% in this study were amikacin (77%), piperacillin-tazobactam (65%), and cephalexin (54%). These three antibiotics are also available in the parenteral form be used as empirical therapy for VAP.
References
1. Spalding MC, Cripps MW, Minshall CT. Ventilator-Associated Pneumonia: New Definitions. Crit Care Clin [Internet]. 2017;33(2):277–92. Available from: http://dx.doi.org/10.1016/j.ccc.2016.12.009
2. Skrupky LP, McConnell K, Dallas J, Kollef MH. A comparison of ventilator-associated pneumonia rates as identified according to the National Healthcare Safety Network and American College of Chest Physicians criteria. Crit Care Med. 2012;40(1):281–4.
3. Kalanuria AA, Zai W, Mirski M. Ventilator-associated pneumonia in the ICU. Crit Care. 2014;18(http//ccforum. com/ content/18/2/208):208.
4. Frieri M, Kumar K, Boutin A. Antibiotic resistance. J Infect Public Health [Internet]. 2017;10(4):369–78. Available from: http://dx.doi.org/10.1016/j.jiph.2016.08.007
5. Saffanah NI, Agustina D, Sutejo R. Postoperative Orthopedic Surgical Site Infection Antibiogram of dr . Soebandi Hospital , Jember in 2019. 2020;110–20.
6. Syahputra RRI, Agustina D, Wahyudi SS. The Sensitivity Pattern of Bacteria Against Antibiotics in Urinary Tract Infection Patients at RSD DR. Soebandi Jember. J Agromedicine Med Sci. 2018;4:171–7.
7. WHO. The role of pharmacist in encouraging prudent use of antibiotics and averting antimicrobial resistance: a review of policy and experience. Heal Technol Pharm Program. 2014;57.
8. Health MD of. About Antibiograms (ANTIMICROBIAL SUSCEPTIBILITIES OF SELECTED PATHOGENS). Infect Dis Epidemiol Prev Control Div [Internet]. 2015;(1/2015):5414. Available from: www.health.state.mn.us
9. Wiggers JB, Xiong W, Daneman N. Sending repeat cultures : is there a role in the management of bacteremic episodes ? ( SCRIBE study ). BMC Infect Dis [Internet]. 2016;1–10. Available from: http://dx.doi.org/10.1186/s12879-016-1622-z
10. Guo S, Xu JJ, Wei YS, Xu JH, Li Y, Xue R. Clinical and molecular characteristics of Klebsiella pneumoniae ventilator-associated pneumonia in mainland China. BMC Infect Dis. 2016;16(1):1–8.
11. Ramírez-Estrada S, Borgatta B, Rello J. Pseudomonas aeruginosa ventilator-associated pneumonia management. Infect Drug Resist. 2016;9:7–18.
12. Tsai CY, Su S hsin, Cheng YH, Chou Y lin, Tsai TH, Lieu AS. Kocuria varians infection associated with brain abscess: A case report. BMC Infect Dis. 2010;10(April):1–5.
13. Pan Y, Song S, Tang X, Ai Q, Zhu D, Liu Z, et al. Streptococcus sp. in neonatal endotracheal tube biofilms is associated with ventilator-associated pneumonia and enhanced biofilm formation of Pseudomonas aeruginosa PAO1. Sci Rep. 2017;7(1):1–12.
14. Widyaningsih R, Buntaran L. Pola Kuman Penyebab Ventilator Associated Pneumonia(VAP) dan Sensitivitas Terhadap Antibiotik di RSAB Harapan Kita. Sari Pediatr. 2016;13(6):384.
15. Taslim E, Maskoen TT. Pola Kuman Terbanyak Sebagai Agen Penyebab Infeksi di Intensive Care Unit pada Beberapa Rumah Sakit di Indonesia The Most Bacterial Patterns as Agent Cause Infection in Intensive Care Unit at some Hospital in Indonesia. Anesth Crit Care. 2016;34:56–62.
16. Herawati F, Irawati L. Terapi Antibiotik pada Infeksi Nosokomial. Bul Rasional [Internet]. 2014;9(2):15–6. Available from http://repository.ubaya.ac.id/id/eprint/28034
